Detection of a new reaction by-product in BDDE cross-linked autoclaved hyaluronic acid hydrogels by LC–MS analysis
Javier Fidalgo,* Pierre-Antoine Deglesne,* Rodrigo Arroyo,* Lilian Sepúlveda,* Evgeniya Ranneva, Philippe Deprez Scientific Department, Skin Tech Pharma Group, Castello D’Empúries, Cataluña, Spain *These authors contributed equally to this work Background: Hyaluronic acid (HA), a naturally occurring polysaccharide, is use